Description:
Multidrug Resistance 1 is inherited as an autosomal incomplete dominant disease. The MDR1 gene codes for the production of a protein known as p-glycoprotein. P-glycoprotein acts as a pump that removes certain drugs and toxins from the body. A mutation in the ABCB1 gene associated with MDR1 prohibits P-glycoprotein’s ability to limit absorption, distribution, and excretion of drugs and allows higher levels of drugs to enter the brain.
Dogs only need to inherit one copy of the MDR1 mutation to be at risk for sensitivity to certain drugs. Dogs with two copies of the MDR1 mutation can have more severe reactions such as excess salivation, tremors, anorexia, blindness and possibly death.
MDR1 affected dogs are at risk of developing neurologic symptoms from several common drugs and you should inform your veterinarian if your dog is a MDR1-carrier or MDR1-affected so they can adjust dosage or provide an alternative medication.
The DNA test is an accurate, convenient, and affordable tool to help breeders avoid producing Multidrug Resistance 1 carrier and affected offspring and significantly reduce the gene frequency in future generations.
This test is available for all dog breeds.
The results confirm 1 of the 3 possible genotypes for the tested dog:
CLEAR (those having two genes from their parents that are mutation free and will not be affected by MDR1).
CARRIER (those having one normal copy of the MDR1 gene, and one mutation. This means that the dog has an increased risk of drug sensitivity).
AFFECTED (those having two copies of the mutated MDR1 gene from their parents and are at risk of adverse drug reactions).
Ingredients
The DNA Sample Collection Kit Contains - 4 x sterile mouth swabs (all 4 for 1 dog), step-by-step sample collection instructions, registration form and return envelope.
Details:
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AffinityDNA Dog Multidrug Resistance 1 (MDR1) DNA Test | Home Sample Collection for 1 Canine | Puppy MDR1 Testing | Results in 7 Working Days | Complete Kit With No Extra Fees
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Imported From: United Kingdom
At BOLO, we work hard to ensure the products you receive are new, genuine, and sourced from reputable suppliers.
Every product in the BOLO catalogue is sourced through our Verified Global Supply Network of verified sellers, authorized distributors or directly from the manufacturer.
Each product undergoes thorough inspection and verification at our consolidation and fulfilment centers to ensure it meets our strict authenticity and quality standards before being shipped and delivered to you.
If you ever have concerns regarding the authenticity of a product purchased from us, please contact Bolo Support. We will review your inquiry promptly and, if necessary, provide documentation verifying authenticity or offer a suitable resolution.
Your trust is our top priority, and we are committed to maintaining transparency and integrity in every transaction.
While we strive to display accurate information, variations in packaging, labeling, instructions, or formulation may occasionally occur due to regional differences or supplier updates. For detailed or manufacturer-specific information, please contact the brand directly or reach out to BOLO Support for assistance.
Unless otherwise stated, all prices displayed on the product page include applicable taxes and import duties.
BOLO operates in accordance with the laws and regulations of Qatar. Any items found to be restricted or prohibited for sale within the Qatar will be cancelled prior to shipment. We take proactive measures to ensure that only products permitted for sale in Qatar are listed on our website.
All items are shipped by air, and any products classified as “Dangerous Goods (DG)” under IATA regulations will be removed from the order and cancelled.
All orders are processed manually, and we make every effort to process them promptly once confirmed. Products cancelled due to the above reasons will be permanently removed from listings across the website.
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Or share with link
https://www.bolo.qa/products/KO0857UZ8XQ
Visit the AffinityDNA Store
AffinityDNA Dog Multidrug Resistance 1 (MDR1) DNA Test | Home Sample Collection for 1 Canine | Puppy MDR1 Testing | Results in 7 Working Days | Complete Kit With No Extra Fees
Imported From: United Kingdom
At BOLO, we work hard to ensure the products you receive are new, genuine, and sourced from reputable suppliers.
Every product in the BOLO catalogue is sourced through our Verified Global Supply Network of verified sellers, authorized distributors or directly from the manufacturer.
Each product undergoes thorough inspection and verification at our consolidation and fulfilment centers to ensure it meets our strict authenticity and quality standards before being shipped and delivered to you.
If you ever have concerns regarding the authenticity of a product purchased from us, please contact Bolo Support. We will review your inquiry promptly and, if necessary, provide documentation verifying authenticity or offer a suitable resolution.
Your trust is our top priority, and we are committed to maintaining transparency and integrity in every transaction.
While we strive to display accurate information, variations in packaging, labeling, instructions, or formulation may occasionally occur due to regional differences or supplier updates. For detailed or manufacturer-specific information, please contact the brand directly or reach out to BOLO Support for assistance.
Unless otherwise stated, all prices displayed on the product page include applicable taxes and import duties.
BOLO operates in accordance with the laws and regulations of Qatar. Any items found to be restricted or prohibited for sale within the Qatar will be cancelled prior to shipment. We take proactive measures to ensure that only products permitted for sale in Qatar are listed on our website.
All items are shipped by air, and any products classified as “Dangerous Goods (DG)” under IATA regulations will be removed from the order and cancelled.
All orders are processed manually, and we make every effort to process them promptly once confirmed. Products cancelled due to the above reasons will be permanently removed from listings across the website.
Description:
Multidrug Resistance 1 is inherited as an autosomal incomplete dominant disease. The MDR1 gene codes for the production of a protein known as p-glycoprotein. P-glycoprotein acts as a pump that removes certain drugs and toxins from the body. A mutation in the ABCB1 gene associated with MDR1 prohibits P-glycoprotein’s ability to limit absorption, distribution, and excretion of drugs and allows higher levels of drugs to enter the brain.
Dogs only need to inherit one copy of the MDR1 mutation to be at risk for sensitivity to certain drugs. Dogs with two copies of the MDR1 mutation can have more severe reactions such as excess salivation, tremors, anorexia, blindness and possibly death.
MDR1 affected dogs are at risk of developing neurologic symptoms from several common drugs and you should inform your veterinarian if your dog is a MDR1-carrier or MDR1-affected so they can adjust dosage or provide an alternative medication.
The DNA test is an accurate, convenient, and affordable tool to help breeders avoid producing Multidrug Resistance 1 carrier and affected offspring and significantly reduce the gene frequency in future generations.
This test is available for all dog breeds.
The results confirm 1 of the 3 possible genotypes for the tested dog:
CLEAR (those having two genes from their parents that are mutation free and will not be affected by MDR1).
CARRIER (those having one normal copy of the MDR1 gene, and one mutation. This means that the dog has an increased risk of drug sensitivity).
AFFECTED (those having two copies of the mutated MDR1 gene from their parents and are at risk of adverse drug reactions).
Ingredients
The DNA Sample Collection Kit Contains - 4 x sterile mouth swabs (all 4 for 1 dog), step-by-step sample collection instructions, registration form and return envelope.
Details:
Similar suggestions by Bolo
More from this brand
Similar items from “DNA Tests”
Share with
Or share with link
https://www.bolo.qa/products/KO0857UZ8XQ